tecovirimat will improve the level or impact of diazepam by impacting hepatic enzyme CYP2C19 metabolism. Use Caution/Monitor. Tecovirimat is actually a weak inhibitor of CYP2C8 and CYP2C19. Keep an eye on for adverse effects if coadministered with sensitive substrates of those enzymes.
Prescribers are strongly advised to consider all sensible methods to make certain that caregivers entirely recognize their purpose and obligations vis a vis the administration of diazepam rectal gel to men and women in their care
topiramate will minimize the level or effect of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
griseofulvin will decrease the level or influence of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
fosaprepitant will raise the stage or influence of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
Continue to keep VALTOCO in a safe place to avoid misuse and abuse. Offering or gifting away VALTOCO may perhaps harm Many others and is also versus the law. Tell your healthcare company Should you have abused or been dependent on alcohol, prescription medicine, or Avenue medication. It is far from recognized if VALTOCO is Risk-free and efficient in little ones underneath six several years of age. Vital Security Data
diazepam will increase the amount or effect of tazemetostat by influencing hepatic/intestinal check here enzyme CYP3A4 metabolism. Use Caution/Keep track of.
diazepam will improve the level or result of lemborexant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Carefully. Reduce nightly dose of lemborexant proposed if coadministered with weak CYP3A4 inhibitors. See drug monograph for certain dosage modification.
Use Caution/Monitor. Ethinyl estradiol may well inhibit the clearance of benzodiazepines that go through oxidation, thus increasing serum concentrations of concomitantly administered benzodiazepines.
Inside of, I maintain VALTOCO and a summary of unexpected emergency contacts. Anyone in my Workplace is familiar with where it is and the way to utilize it as Component of my Seizure Action Plan.
fludrocortisone will lower the level or result of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
VALTOCO can be a prescription medication utilized for the shorter-phrase treatment method of seizure clusters (also referred to as “episodes of Repeated seizure activity” or “acute repetitive seizures”) in patients 6 yrs of age and older. VALTOCO is really a federally managed material (CIV) as it is usually abused or cause dependence.
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“This scared the lifestyle out of me. I had been over a day-to-day seizure medication, confident, but I nevertheless struggled with seizure Handle. My mom had diazepam rectal gel to make use of as a direct-use seizure medication in the event of episodes of Regular seizures, but who wants their Mother making use of that on them? It was not great. I yearned being independent and manage points on my own.”